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Catalysing chemical reactions with enzymes

Proteins are one of four main classes of biomolecules in living organisms. The others are lipids, which form our membranes, nucleic acids (DNA and RNA), which carry and carry out our instructions, and carbohydrates, which not only give us energy but are also sometimes involved in signalling processes and other cellular processes. Proteins are the most diverse of these four biomolecules.

4 main classes of biomolecules in living organisms diagram.

Biomolecules

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There are four main classes of biomolecules in living organisms.

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Enzymes are proteins that catalyse chemical reactions – they are biocatalysts. Catalysts make chemical reactions happen much more quickly than is possible spontaneously. Biocatalysts naturally carry out their action in living organisms. Most biochemical reactions, if left to their own devices, will take millions of years to occur but can occur within cells in milliseconds due to the action of enzymes.

Enzyme malate dehydrogenase in electron transport chain

Enzyme malate dehydrogenase

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The enzyme malate dehydrogenase is used in the electron transport chain in cellular respiration. This reaction is part of many metabolic pathways including the Krebs cycle.

Still image created from animated footage from PDB-101. PDB-101 is the educational portal of RCSB Protein Data Bank.

 

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There are thousands of enzymes within each living organism and each has a specific role – controlling essential biological and biochemical reactions by working with specific substrates to create specific products.

How enzymes work

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This animation provides a visual explanation about how enzymes catalyse cellular processes. 

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Some common enzymes found in animals are used in the digestion system. Amylase is found in saliva and helps the breakdown of starches into sugars. Trypsin is found in the small intestine and breaks down protein into amino acids. Lipases are a group of enzymes that help digest fat in the gut.

Nature of science

The animation within this article is a model created to help visualise the action of enzymes. Scientists often use models to help build and communicate their understandings about the world.

Related content

Learn more about enzymes:

Enzymes in the lab

  • Restriction enzymes

Enzymes associated with digestion and food

  • Digestive enzymes

  • Rate of digestion

  • Fruit enzyme uses

  • Fruit enzymes tenderise meat

Enzymes in industry

  • Enzymes in washing powders

  • Improving enzymes

Enzymes and medicine

  • Directed evolution

  • Improving enzymes to help fight cancer

Enzymes in extreme environments

  • Extremophilic microorganisms

  • Uses of extremophilic microorganisms

Learn more about proteins

  • Proteins – what they are and how they are made

  • Role of proteins in the body

Activity ideas

Explore the action of enzymes

  • Enzyme action 

  • Salivary amylase and starch 

  • Lactose intolerance

  • A comparison of home-made marinades.

 

Glossary

Published: 8 February 2022
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