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Zebrafish and genetic research

Zebrafish are small tropical fish being used to help genetic research into human cancers and developmental diseases.

A female specimen of a zebrafish (Danio rerio)

Zebrafish

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Zebrafish are an example of a model organism. Model organisms are non-human species used by scientists to better understand particular biological research questions.

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Listen to this RNZ interview with Dr Julia Horsfield and PhD student Jenny Rhodes, looking at Zebrafish and genetic research.

Zebrafish are a good model to use for studying human diseases because their eggs are transparent and external to the parent. This means you can see the embryo growing in real time. Scientists can gain insights into the development of human diseases by manipulating genes in the embryo and studying their development.

This article, Secret of body orientation discovered, gives another example of the importance of zebrafish in research.

The zebrafish life cycle

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Zebrafish - from egg to fry to adult to egg.

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See the video conference: Dr Love's zebrafish.

Julia Horsfield and PhD student Jenny Rhodes from the Dunedin School of Medicine, where they have recently opened a zebrafish facility, explain their research into human cancers using zebrafish as a model. Their aim is to add knowledge that will generate effective cures for human cancers, particularly breast cancer.

Programme details: Our Changing World

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Published: 16 September 2009
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